Author Title Type [ Year(Asc)]
Filters: Author is Jordan N Smith  [Clear All Filters]
2023
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Tilton SC, Vertel EA, Tidwell LG, et al.. Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts. Toxicol Appl Pharmacol. 2023 ;460:116377.
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Labut EM, Vertel EA, Tidwell LG, et al.. Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing. Chem Biol Interact. 2023 ;382:110608.
2022
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Anderson KA, Tidwell LG, Ognibene TJ, et al.. Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [C]-BaP. Environ Int. 2022 ;159:107045.
Smith JN, Gaither KA, Pande P. Competitive Metabolism of Polycyclic Aromatic Hydrocarbons (PAHs): An Assessment Using In Vitro Metabolism and Physiologically Based Pharmacokinetic (PBPK) Modeling. Int J Environ Res Public Health. 2022 ;19(14).
2021
Monica L Vermillion Maier, Siddens LK, Uesugi S, Choi J, Leonard SW, Pennington JM, Smith JN, et al.. 3,3'-Diindolylmethane Exhibits Significant Metabolism after Oral Dosing in Humans. Drug Metab Dispos. 2021 ;49(8):694-705.
Stoddard EG, Nag S, Martin J, Tyrrell KJ, Gibbins T, Anderson KA, et al.. Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice. Chem Res Toxicol. 2021 ;34(9):2145-2156.
Pande P, Madeen EP, Williams DE, Crowell SRitger, Ognibene TJ, Turteltaub KW, et al.. Translating dosimetry of Dibenzo[def,p]chrysene (DBC) and metabolites across dose and species using physiologically based pharmacokinetic (PBPK) modeling. Toxicol Appl Pharmacol. 2021 ;:115830.
2019
Stoddard EG, Killinger BJ, Nag S, Martin J, Corley RA, Smith JN. Benzo[ a]pyrene Induction of Glutathione S-Transferases: An Activity-Based Protein Profiling Investigation. Chem Res Toxicol. 2019 ;32(6):1259-1267.
Madeen EP, Siddens LK, Uesugi S, McQuistan TJ, Corley RA, Smith JN, et al.. Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing. Toxicol Appl Pharmacol. 2019 ;364:97-105.
2018
Stoddard EG, Volk RF, Carson JP, Ljungberg CM, Murphree TA, Smith JN, et al.. Multifunctional Activity-Based Protein Profiling of the Developing Lung. J Proteome Res. 2018 ;17(8):2623-2634.
Hummel JM, Madeen EP, Siddens LK, Uesugi S, McQuistan TJ, Anderson KA, et al.. Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction. Food Chem Toxicol. 2018 ;115:136-147.
2017
Stoddard EG, Killinger BJ, Nair RN, Sadler NC, Volk RF, Purvine SO, et al.. Activity-Based Probes for Isoenzyme- and Site-Specific Functional Characterization of Glutathione S-Transferases. J Am Chem Soc. 2017 ;139(45):16032-16035.
Smith JN, Mehinagic D, Nag S, Crowell SRitger, Corley RA. In vitro metabolism of benzo[a]pyrene-7,8-dihydrodiol and dibenzo[def,p]chrysene-11,12 diol in rodent and human hepatic microsomes. Toxicol Lett. 2017 ;269:23-32.
2016
Sadler NC, Nandhikonda P, Webb-Robertson B-J, Ansong C, Anderson LN, Smith JN, et al.. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development. Drug Metab Dispos. 2016 ;44(7):984-91.