The Superfund Research Center

Environmental exposures, including chemical contaminants and heat stress, pose a major risk to kidney health, particularly contributing to an emerging epidemic of chronic kidney disease in tropical farming communities. I will discuss our community-engaged, bench-to-bedside approach investigating how these exposures contribute to disease onset and progression in impacted communities and will highlight the use of zebrafish (Danio rerio) as a mechanistic model and a screening tool to inform adult and pediatric cohort studies.