Author Title Type [ Year(Desc)]
Filters: Keyword is Microsomes, Liver  [Clear All Filters]
2014
Crowell SRitger, Hanson-Drury S, Williams DE, Corley RA. In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes. Toxicol Lett. 2014 ;228(1):48-55.
2016
Sadler NC, Nandhikonda P, Webb-Robertson B-J, Ansong C, Anderson LN, Smith JN, et al.. Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development. Drug Metab Dispos. 2016 ;44(7):984-91.
2017
Smith JN, Mehinagic D, Nag S, Crowell SRitger, Corley RA. In vitro metabolism of benzo[a]pyrene-7,8-dihydrodiol and dibenzo[def,p]chrysene-11,12 diol in rodent and human hepatic microsomes. Toxicol Lett. 2017 ;269:23-32.
2021
Stoddard EG, Nag S, Martin J, Tyrrell KJ, Gibbins T, Anderson KA, et al.. Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice. Chem Res Toxicol. 2021 ;34(9):2145-2156.
2022
Smith JN, Gaither KA, Pande P. Competitive Metabolism of Polycyclic Aromatic Hydrocarbons (PAHs): An Assessment Using In Vitro Metabolism and Physiologically Based Pharmacokinetic (PBPK) Modeling. Int J Environ Res Public Health. 2022 ;19(14).
2024
Gaither KA, Garcia WL, Tyrrell KJ, Wright AT, Smith JN. Activity-Based Protein Profiling to Probe Relationships between Cytochrome P450 Enzymes and Early-Age Metabolism of Two Polycyclic Aromatic Hydrocarbons (PAHs): Phenanthrene and Retene. Chem Res Toxicol. 2024 ;37(5):711-722.