Author Title Type [ Year(Desc)]
Filters: Author is David E Williams and Keyword is Humans  [Clear All Filters]
2014
Crowell SRitger, Hanson-Drury S, Williams DE, Corley RA. In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes. Toxicol Lett. 2014 ;228(1):48-55.
2015
Harper TA, Morré J, Lauer FT, McQuistan TJ, Hummel JM, Burchiel SW, et al.. Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS. Mutat Res Genet Toxicol Environ Mutagen. 2015 ;782:51-6.
Madeen EP, Corley RA, Crowell SRitger, Turteltaub KW, Ognibene TJ, Malfatti M, et al.. Human in Vivo Pharmacokinetics of [(14)C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing. Chem Res Toxicol. 2015 ;28(1):126-34.
2016
Teeguarden JG, Tan Y-M, Edwards SW, Leonard JA, Anderson KA, Corley RA, et al.. Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework. Environ Sci Technol. 2016 ;50(9):4579-86.
Madeen EP, Ognibene TJ, Corley RA, McQuistan TJ, Henderson MC, Baird WM, et al.. Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry. Chem Res Toxicol. 2016 ;29(10):1641-1650.
2017
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, et al.. Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Mol Carcinog. 2017 ;56(1):163-171.
Madeen EP, Williams DE. Environmental PAH exposure and male idiopathic infertility: a review on early life exposures and adult diagnosis. Rev Environ Health. 2017 ;32(1-2):73-81.
2018
Hummel JM, Madeen EP, Siddens LK, Uesugi S, McQuistan TJ, Anderson KA, et al.. Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction. Food Chem Toxicol. 2018 ;115:136-147.
2022
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Anderson KA, Tidwell LG, Ognibene TJ, et al.. Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [C]-BaP. Environ Int. 2022 ;159:107045.
2023
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Tilton SC, Vertel EA, Tidwell LG, et al.. Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts. Toxicol Appl Pharmacol. 2023 ;460:116377.