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Filters: Author is David E Williams and Keyword is Benzopyrenes  [Clear All Filters]
2016
Madeen EP, Ognibene TJ, Corley RA, McQuistan TJ, Henderson MC, Baird WM, et al.. Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry. Chem Res Toxicol. 2016 ;29(10):1641-1650.
2015
Harper TA, Morré J, Lauer FT, McQuistan TJ, Hummel JM, Burchiel SW, et al.. Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS. Mutat Res Genet Toxicol Environ Mutagen. 2015 ;782:51-6.
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, et al.. Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse. Toxicol Appl Pharmacol. 2015 ;287(2):149-160.
Madeen EP, Corley RA, Crowell SRitger, Turteltaub KW, Ognibene TJ, Malfatti M, et al.. Human in Vivo Pharmacokinetics of [(14)C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing. Chem Res Toxicol. 2015 ;28(1):126-34.
2014
Crowell SRitger, Hanson-Drury S, Williams DE, Corley RA. In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes. Toxicol Lett. 2014 ;228(1):48-55.
2013
Shorey LE, Madeen EP, Atwell LL, Ho E, Löhr CV, Pereira CB, et al.. Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane. Toxicol Appl Pharmacol. 2013 ;270(1):60-9.
Crowell SRitger, Sharma AK, Amin SG, Soelberg JJ, Sadler NC, Wright AT, et al.. Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice. Toxicol Sci. 2013 ;135(1):48-62.
2012
Siddens LK, Larkin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, et al.. Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicol Appl Pharmacol. 2012 ;264(3):377-86.
Shorey LE, Castro DJ, Baird WM, Siddens LK, Löhr CV, Matzke MM, et al.. Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring. Cancer Lett. 2012 ;317(1):49-55.
2011
Crowell SRitger, Amin SG, Anderson KA, Krishnegowda G, Sharma AK, Soelberg JJ, et al.. Preliminary physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents. Toxicol Appl Pharmacol. 2011 ;257(3):365-76.
2006
Yu Z, Löhr CV, Fischer KA, Louderback MA, Krueger SK, Dashwood RH, et al.. In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor. Cancer Res. 2006 ;66(2):755-62.