Author Title Type [ Year(Desc)]
Filters: Author is Lisbeth K Siddens  [Clear All Filters]
2012
Siddens LK, Larkin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, et al.. Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicol Appl Pharmacol. 2012 ;264(3):377-86.
Shorey LE, Castro DJ, Baird WM, Siddens LK, Löhr CV, Matzke MM, et al.. Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring. Cancer Lett. 2012 ;317(1):49-55.
2013
Larkin A, Siddens LK, Krueger SK, Tilton SC, Waters KM, Williams DE, et al.. Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin. Toxicol Appl Pharmacol. 2013 ;267(2):192-9.
2015
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, et al.. Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse. Toxicol Appl Pharmacol. 2015 ;287(2):149-160.
Tilton SC, Siddens LK, Krueger SK, Larkin A, Löhr CV, Williams DE, et al.. Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential. Toxicol Sci. 2015 ;146(1):135-45.
2017
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, et al.. Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Mol Carcinog. 2017 ;56(1):163-171.
2018
Hummel JM, Madeen EP, Siddens LK, Uesugi S, McQuistan TJ, Anderson KA, et al.. Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction. Food Chem Toxicol. 2018 ;115:136-147.
2019
Chang Y, Siddens LK, Heine LK, Sampson DA, Yu Z, Fischer KA, et al.. Comparative mechanisms of PAH toxicity by benzo[a]pyrene and dibenzo[def,p]chrysene in primary human bronchial epithelial cells cultured at air-liquid interface. Toxicol Appl Pharmacol. 2019 ;:114644.
Madeen EP, Siddens LK, Uesugi S, McQuistan TJ, Corley RA, Smith JN, et al.. Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing. Toxicol Appl Pharmacol. 2019 ;364:97-105.
2020
Chang Y, Huynh CThanh Thu, Bastin KM, Rivera BN, Siddens LK, Tilton SC. Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures. Toxicol In Vitro. 2020 ;69:104991.
2021
Monica L Vermillion Maier, Siddens LK, Uesugi S, Choi J, Leonard SW, Pennington JM, Smith JN, et al.. 3,3'-Diindolylmethane Exhibits Significant Metabolism after Oral Dosing in Humans. Drug Metab Dispos. 2021 ;49(8):694-705.
2022
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Anderson KA, Tidwell LG, Ognibene TJ, et al.. Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [C]-BaP. Environ Int. 2022 ;159:107045.
2023
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Tilton SC, Vertel EA, Tidwell LG, et al.. Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts. Toxicol Appl Pharmacol. 2023 ;460:116377.
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Labut EM, Vertel EA, Tidwell LG, et al.. Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing. Chem Biol Interact. 2023 ;382:110608.